The anti-tumor effects of curcumin on the p53 pathway of human endometrial carcinoma cells

Touma, Tina

dc.contributor.author	Touma, Tina
dc.date.accessioned	2021-01-16T09:58:45Z
dc.date.available	2021-01-16T09:58:45Z
dc.date.issued	2020
dc.identifier.citation	Touma, T. (2020). The anti-tumor effects of curcumin on the p53 pathway of human endometrial carcinoma cells (Master's thesis, Notre Dame University-Louaize, Zouk Mosbeh, Lebanon). Retrieved from http://ir.ndu.edu.lb/123456789/1273
dc.identifier.uri	http://ir.ndu.edu.lb/123456789/1273
dc.description	M.S. -- Faculty of Natural and Applied Sciences, Notre Dame University, Louaize, 2020; " A thesis presented in partial fulfillment of the requirements for the degree of Master of Science"; Includes bibliographical references (pages 27-30).
dc.description.abstract	One of the clinically major gynecological cancers is endometrial carcinoma that develops from the lining of the uterus. During the past years, different approaches have been developed to treat endometrial carcinoma, among which natural herbal medicine has recently faired as an effective method. The yellow Indian spice known as curcumin has been extolled for its healing powers and has recently been adopted for investigation by the scientific community as a potent anti-cancerous agent. Curcumin possesses anticancerous effects by targeting several important players in cell signaling pathways such as Ras, MAPKs, ERK, Wnt-β, PI3K Akt, and p53.This paper highlights all studies pertaining to curcumin and its effect on endometrial cancer, but no study was found to demonstrate the effect of curcumin on the p53 pathway of endometrial cancer cells. This study aims to show how curcumin affects endometrial cancer through targeting the p53	en_US
dc.format.extent	ix, 31 pages : illustrations (some color)
dc.language.iso	en	en_US
dc.publisher	Notre Dame University-Louaize	en_US
dc.rights	Attribution-NonCommercial-NoDerivs 3.0 United States	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/us/	*
dc.subject.lcsh	Curcumin--Therapeutic use
dc.subject.lcsh	Endometrium--Cancer
dc.subject.lcsh	p53 protein
dc.title	The anti-tumor effects of curcumin on the p53 pathway of human endometrial carcinoma cells	en_US
dc.type	Thesis	en_US
dc.rights.license	This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 United States License. (CC BY-NC 3.0 US)
dc.contributor.supervisor	El Khoury, Diala, Ph.D.	en_US
dc.contributor.department	Notre Dame University-Louaize. Department of Sciences