Department of Sciences: Recent submissions

  • Nassif, Nathalie (Notre Dame University-Louaize, 2020)
    Chronic moderate alcohol consumption has been implicated in promoting bone health in acyclic (postmenopausal) women via increasing bone mineral density. To our knowledge, no studies investigated the potential effects of ethanol on the bone-specific markers osteocalcin and RANKL which are important in regulating osteoblast - osteoclast activity and bone metabolism. Therefore, the aim of the study was to look into RANKL expression in serum and RANKL and osteocalcin expression in the femoral neck following chronic alcohol consumption of 12% v/v ethanol in water in acyclic C57BL/6 mice. Female ...
  • Sahakian, Joseph Ohannes (Notre Dame University-Louaize, 2020-09)
    Ceratitis capitata or the Mediterranean fruit fly (medfly) is a highly invasive and destructive pest due to its tolerance of various climatic and environmental conditions as well as broad host range, including hundreds of fruits and vegetables. Medfly has a great economic impact on fruit production, national market and world trade. The population in Lebanon has been on the rise since 2007 due to several factors including optimal climate and host conditions, insecticide resistance, and negligent regulatory and detection measures during fruit harvest and transportation. Medfly infestation in Lebanon ...
  • Ghosn, Marc (Notre Dame University-Louaize, 2020-07)
    An extraction protocol for saponins of Styrax Officinalis plant was adopted, modified and successfully applied. The extract obtained was tested by stabilizing Oil-in-Water emulsions. Ethanol extraction and successful one-step partial purification using AB-8 adsorption column chromatography yielded positive colorimetric (Vanillin – Sulfuric Acid) TLC results. The 3D structure of the four Styrax Officinalis saponins reported in the literature were rendered for the first time, and their partitioning properties exclusively acquired using Marvin Sketch chemical drawing software. 10% w/w Sunflower Oil ...
  • Nassar, Marc Gerges (Notre Dame University-Louaize., 2020)
    The HPG axis interacts with the Sertoli and Leydig cells to ensure the proper functioning of the male reproductive system. Environmental insults, which are becoming increasingly more common, affect the sensitive male reproductive system in harmful ways. Therefore, the aim of this thesis was to, analyze a network of the paternally imprinted infertility genes shared between the HPG axis and the Sertoli and Leydig cells. With this network in place, we aimed to develop a cell culture system that would allow the evaluation of the effects of certain environmental contaminants such as mycotoxins on ...
  • Hindieh, Pascale (Notre Dame University-Louaize., 2020)
    Sexual activity constitute in the life of the adolescent, a risk-taking and possibly health-compromising behavior. Since unfortunately, knowledge about sexuality is often acquired after sexual activity has begun, sexually transmitted diseases (STDs) should be given high priority in health care and in education. Sexual education is an indispensable need, especially for adolescents, in order to protect them from irresponsible and non-conscious behavior. In the areas of adolescent sexual behavior, sexual education and knowledge, it is imperative and of paramount importance that the health-care ...
  • Dib, Kevin (Notre Dame University-Louaize, 2020-10)
    In this work, Silver Nanoparticles (AgNPs) were synthesized in water using either polymer assisted chemical reduction synthesis method or green synthesis. The obtained AgNPs were characterized by Dynamic Light Scattering (DLS) and UV-visible spectroscopy (UV-vis), and further tested for antibacterial activity to evaluate their potential use in wound healing. At first polyvinylpyrrolidone (PVP 10 KD) and Low-Molecular Weight Chitosan were used as coating agents during the reduction of silver nitrate with a strong reducing agent sodium borohydride (NaBH4). Our DLS results demonstrated that ...
  • Fayjaloun, Salma (Notre Dame University-Louaize, 2019)
    Fusarium mycotoxins are natural contaminants of various commodities representing significant problem worldwide. Since beauvericin (BEA), one of the fusarium toxins, represents a major concern because of its potential toxicity in humans and animal health, and its high presence in feed and food commodities, the present study was carried out to evaluate the effect of BEA on cell viability, proliferation, morphology and gene expression using spermatogonial stem cells (SSCs). First, SSCs were isolated from fresh sheep testis under aseptic technique. Isolated SSCs were cultured for 36 hours at 5% CO2. ...
  • Rhaim, Zeina Antoine (Notre Dame University-Louaize, 2019)
    Known as polymorphonuclear leukocytes (PMNs), neutrophils have been shown to play a regulatory role in healing injuries and resolving infections. Although the immune response (IR) of neutrophils in bacterial and fungal infections is well understood, their impact during sporozoite infection is much less studied. This project investigates the role of neutrophils in recognizing Plasmodium berghei sporozoites in an effort to understand the mechanism of sporozoites’ IR evasion and spread of malaria infection in the blood circulation. Plasmodium berghei GFP-expressing sporozoites were purified from ...
  • Ismail, Diana (Notre Dame University-Louaize, 2019-02)
    In this thesis, we have restudied a sample chosen by (Lusso & Risaliti, 2016) consisting of a set of 2,153 unique quasars given by two source catalogues: 3XMM-DR5 (Rosen et al., 2016) and DR7 catalogue (Shen et al., 2011). Quasars serve science in two different ways: 1) Understanding accretion physics by studying the physical mechanism occuring between the disk and cloud corona, and 2) they are good cosmological probes in distance estimation reaching redshifts ~ 7 (Mortlock et al., 2011). A physical relation has been observed between the optical-UV disk and the X-ray corona through a log-log ...
  • Najem-Moussa, Wadiha (Notre Dame University-Louaize, 2019-02-02)
    During recent years, the practice of administering antibiotics to animal feed at sub-therapeutic levels has raised concern with consumers because of the apparent increase of antibiotic-resistant bacteria in the human food chain. Researchers have found that probiotics composed of naturally occurring beneficial live microbes such as bacteria (lactobacilli) could be the novel growth promoters. Supplementing poultry diet with probiotics has been found to improve growth performance, feed conversion efficiency, and immune responses, and help in combating enteric pathogens. The aim of this study is ...

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