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Browsing Theses and Dissertations by Author "El Khoury, Diala, Ph.D."

Browsing Theses and Dissertations by Author "El Khoury, Diala, Ph.D."

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  • Touma, Tina (Notre Dame University-Louaize, 2020)
    One of the clinically major gynecological cancers is endometrial carcinoma that develops from the lining of the uterus. During the past years, different approaches have been developed to treat endometrial carcinoma, among which natural herbal medicine has recently faired as an effective method. The yellow Indian spice known as curcumin has been extolled for its healing powers and has recently been adopted for investigation by the scientific community as a potent anti-cancerous agent. Curcumin possesses anticancerous effects by targeting several important players in cell signaling pathways ...
  • Jerdy, Jouliana (Notre Dame University-Louaize, 2020-12)
    Yerba Mate (Ilex paraguariensis) is a beverage that is highly consumed by certain communities in Lebanon. Several studies have shown the benefits of yerba mate consumption on one's health. Also, Lebanese add to their hot drink some medicinal plants that have been acquired by the society from the Arabian folk medicine. Many studies have been conducted, yet little is known about its effect on the Lebanese health, as they have been consuming it for almost 100 years. Therefore, this study was done to assess the use of yerba mate and medicinal plants. A questionnaire was distributed among 200 local ...
  • Fayjaloun, Salma (Notre Dame University-Louaize, 2019)
    Fusarium mycotoxins are natural contaminants of various commodities representing significant problem worldwide. Since beauvericin (BEA), one of the fusarium toxins, represents a major concern because of its potential toxicity in humans and animal health, and its high presence in feed and food commodities, the present study was carried out to evaluate the effect of BEA on cell viability, proliferation, morphology and gene expression using spermatogonial stem cells (SSCs). First, SSCs were isolated from fresh sheep testis under aseptic technique. Isolated SSCs were cultured for 36 hours at 5% CO2. ...
  • Tohme, Celine (Notre Dame University-Louaize, 2016)
    Several studies have shown a link between pesticide exposure and neurological problems. In the present study, we show the effect of twenty common pesticides (dieldrin, rotenone, endosulfan, penconazole, trifiuralin, dicofol, chloropropham, hexachlorobenzene, thiamethoxam, dimethoate, maneb, p,p' -DDE, paraquat, permethrin, chlorfenapyr, propanil, kresoxim-methyl, boscalid, triadimefon, lambda-cyhalothrin) on myelin gene expression (PLP and MBP) in oligodendrocytes. We first studied the toxicology of each chemical to determine the doses to consider by calculating the ration of dead to living ...

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