In this study, gold nanoparticles (AuNPs) were synthesized in water and characterized using ultraviolet-visible spectroscopy (UV-Vis), dynamic light scattering (DLS) and Zeta potential analysis. AuNPs were coated with thiol functionalized polyethylene glycol (PEG-SH) and scFvD2B (antibody fragment of D2B mAb) well known to recognize the extracellular epitope of the human prostate specific membrane antigen (hPSMA). In fact, scFvD2B binds PSMA and induces its endocytosis, thereby marking PSMA as a docking site for the delivery of therapeutic agents. AuNPs successful coating was confirmed by DLS ...