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Browsing Theses and Dissertations by Author "Rhaim, Zeina Antoine"

Browsing Theses and Dissertations by Author "Rhaim, Zeina Antoine"

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  • Rhaim, Zeina Antoine (Notre Dame University-Louaize, 2019)
    Known as polymorphonuclear leukocytes (PMNs), neutrophils have been shown to play a regulatory role in healing injuries and resolving infections. Although the immune response (IR) of neutrophils in bacterial and fungal infections is well understood, their impact during sporozoite infection is much less studied. This project investigates the role of neutrophils in recognizing Plasmodium berghei sporozoites in an effort to understand the mechanism of sporozoites’ IR evasion and spread of malaria infection in the blood circulation. Plasmodium berghei GFP-expressing sporozoites were purified from ...

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