Sleep restriction is now considered to be a worldwide epidemic, as over 20% of people around the world are sleep deprived. Although sleep deprivation is now an overlooked feature of modern societies, it entails considerable adverse effects on physiological systems, one being energy homeostasis. A corpus of research has demonstrated that leptin, a key hormone that conveys the body's energy status to the brain, decreases after sleep restriction, which may partly account for the associated alteration in body metabolism; however little information is available regarding the underlying ...