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Browsing Theses and Dissertations by Subject "Nanoparticles"

Browsing Theses and Dissertations by Subject "Nanoparticles"

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  • Customized D2B coated gold nanoparticles : promising targeting agents against prostate cancer 
    Sarkis, Monira (Notre Dame University-Louaize, 2018)
    Gold nanoparticles (AuNPs) with an estimate diameter of 25 nm have been synthesized and characterized using ultraviolet-visible spectroscopy (UV-Vis), dynamic light scattering (DLS) and Zeta potential measurements. AuNPs were coated with D2B, a monoclonal antibody recognizing an extracellular epitope of the human prostate specific membrane antigen (hPSMA). Binding of D2B to PSMA induces endocytosis of the latter, thereby marking PSMA as a docking site for the delivery of therapeutic agents. To attain a stabilized and covalent bond between D2B and AuNPs, the sulthydryl group (SH) in a cysteine ...
  • Green synthesis of zero valent Iron nanoparticles using malva extract and their antimicrobial activity 
    Koliana, Rita (2022)
    Green synthesis of metallic nanoparticles has accumulated an ultimate interest over the last decade due to their distinctive properties that make them applicable in various fields of science and technology. Metal nanoparticles that are synthesized by using plants have emerged as nontoxic and ecofriendly. In the current study, the optimal reaction condition for the synthesis of zero valent iron nanoparticles using Malva extract was developed. For the first time, aqueous extract of Malva parviflora was used as a sustainable source of reducing and capping agents to synthesize zero valent iron ...
  • Synthesis and characterization of nanoparticles for potential applications in wound healing 
    Dib, Kevin (Notre Dame University-Louaize, 2020-10)
    In this work, Silver Nanoparticles (AgNPs) were synthesized in water using either polymer assisted chemical reduction synthesis method or green synthesis. The obtained AgNPs were characterized by Dynamic Light Scattering (DLS) and UV-visible spectroscopy (UV-vis), and further tested for antibacterial activity to evaluate their potential use in wound healing. At first polyvinylpyrrolidone (PVP 10 KD) and Low-Molecular Weight Chitosan were used as coating agents during the reduction of silver nitrate with a strong reducing agent sodium borohydride (NaBH4). Our DLS results demonstrated that ...

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