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A comparison of 15N proline and 13C for monitoring protein biosynthesis in the skin

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dc.contributor.author Doumit, Jacqueline
dc.contributor.author Frey, Jacques
dc.contributor.author Chamson, Annette
dc.contributor.author Perier, Christian
dc.date.accessioned 2019-03-11T07:24:45Z
dc.date.available 2019-03-11T07:24:45Z
dc.date.issued 1999
dc.identifier.citation Doumit, J., Le, J., Frey, J., Chamson, A., & Perier, C. (1999) A comparison of 15N proline and 13C leucine for monitoring protein biosynthesis in the skin. Amino Acids. 16, 107-111 en_US
dc.identifier.other https://link.springer.com/article/10.1007/BF01321530 https://link.springer.com/content/pdf/10.1007%2FBF01321530.pdf
dc.identifier.uri http://ir.ndu.edu.lb/123456789/960
dc.description.abstract The tracers L 15N-proline and L(1-13C)-leucine were used to explore the synthesis of skin proteins in vivo in rabbits. They orally received a single dose containing an equimolecular mixture of L(1-13C)-leucine and L15N-proline. The changes in the amounts of these tracers in blood and skin were monitored for a total of 8h. The data showed the appearance of the two tracers in blood within 15min and their clearance in 8h. They were both rapidly (15min) incorporated into skin proteins, but more proline was incorporated than leucine. We therefore consider L 15N -proline to be a better tracer than L(1-13C)-leucine for studying protein metabolism in the skin. en_US
dc.description.abstract PDF file (5 p.)
dc.language.iso English en_US
dc.publisher Springer-Verlag en_US
dc.rights Attribution-NonCommercial-NoDerivs 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/us/ *
dc.subject Tissue protein synthesis en_US
dc.subject.lcsh Amino acids
dc.subject.lcsh Stable isotopes
dc.subject.other Protein Biosynthesis
dc.title A comparison of 15N proline and 13C for monitoring protein biosynthesis in the skin en_US
dc.type Article en_US
dc.provenance Lebanon
dc.provenance France


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